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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STK4
All Species:
34.55
Human Site:
S21
Identified Species:
58.46
UniProt:
Q13043
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13043
NP_006273.1
487
55630
S21
L
K
K
L
D
E
D
S
L
T
K
Q
P
E
E
Chimpanzee
Pan troglodytes
XP_001153224
503
57116
S37
L
K
K
L
D
E
D
S
L
T
K
Q
P
E
E
Rhesus Macaque
Macaca mulatta
A4K2T0
487
55587
S21
L
K
K
L
D
E
D
S
L
T
K
Q
P
E
E
Dog
Lupus familis
XP_534432
487
55507
S21
L
K
K
L
D
E
D
S
L
T
K
Q
P
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI11
487
55523
S21
L
K
K
L
D
E
D
S
L
T
K
Q
P
E
E
Rat
Rattus norvegicus
O54748
491
56103
S18
L
K
K
L
S
E
D
S
L
T
K
Q
P
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518508
281
31761
Chicken
Gallus gallus
Q5ZJK4
486
55318
S20
L
K
K
L
D
E
D
S
L
T
K
Q
P
E
E
Frog
Xenopus laevis
Q6PA14
485
55246
S21
L
K
K
L
S
E
E
S
L
N
K
Q
P
E
E
Zebra Danio
Brachydanio rerio
Q7ZUQ3
492
56062
L18
K
K
L
S
E
D
S
L
T
K
Q
P
E
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T0S6
669
75091
S33
L
K
K
L
S
E
E
S
L
L
Q
P
P
E
K
Honey Bee
Apis mellifera
XP_393691
465
52970
Q18
S
E
E
S
L
T
R
Q
P
E
E
V
F
D
I
Nematode Worm
Caenorhab. elegans
Q9NB31
497
55620
A26
G
F
K
L
D
S
S
A
L
N
K
P
P
E
E
Sea Urchin
Strong. purpuratus
XP_781787
488
55060
A18
L
K
K
L
S
E
D
A
L
T
K
E
P
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
99.3
97.3
N.A.
97.3
78
N.A.
55.8
92.1
76.5
77
N.A.
45.4
62.4
52.3
64.9
Protein Similarity:
100
95.8
99.7
98.9
N.A.
98.5
89.6
N.A.
57.2
96.5
86.8
87.4
N.A.
58.5
77.8
68.4
79.1
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
0
100
80
13.3
N.A.
60
0
53.3
80
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
0
100
86.6
33.3
N.A.
80
26.6
60
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
50
8
58
0
0
0
0
0
0
8
0
% D
% Glu:
0
8
8
0
8
72
15
0
0
8
8
8
8
86
72
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
8
79
79
0
0
0
0
0
0
8
72
0
0
0
8
% K
% Leu:
72
0
8
79
8
0
0
8
79
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
22
79
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
15
58
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
15
29
8
15
65
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
8
58
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _